Table 2. Disease characteristics and radiation dose to the retina of irradiated subjects.
OD | OS | |||||||||
No. | Disease Site | Histology | Stage | Prescription Dose† | Mean Dose (Gy)* | Max Dose (Gy)* | % of retina receiving > 45 Gy | Mean Dose* | Max Dose* | % of retina recei ving > 45 Gy |
1 | L ethmoid sinus | Adenocarci noma | T4aN0M0 | 62.4 Gy/1.2 Gy BID | 18.4 | 44.1 | 0 | 29.9 | 54.8 | 19.5 |
2 | R maxillary sinus | Adenoid cystic carcinoma | T4bN0M0 | 62 Gy/2 Gy | 44.4 | 64.5 | 51.0 | 3.58 | 17.8 | 0 |
3 | Nasopharynx | Nasopharyngeal carcinoma, WHO type III | T4N2cM0 | 68 Gy/2 Gy | 55.6 | 69.4 | 85.2 | 35.1 | 54.9 | 12.2 |
4 | L maxillary sinus | Squamous cell carcinoma | T4bN0M0 | 70.2 Gy/1.8 Gy | 8.23 | 35 | 0 | 59.7 | 74 | 93.8 |
5 | R ethmoid sinus | Sinonasal undifferentiated carcinoma | T4aN0M0 | 63 Gy/2 Gy | 47.6 | 60.2 | 67.9 | 11.8 | 40.7 | 0 |
6 | R ethmoid sinus | Sinonasal undifferentiated carcinoma | T2N0M0 | 59.4 Gy /1.8 Gy | 30.0 | 60.9 | 22.6 | 16.2 | 50.7 | 5.1 |
7 | L maxillary and ethmoid sinuses | Neuroendocrine carcinoma | T4bN0M0 | 60 Gy/2 Gy | 23.7 | 51 | 1.5 | 58.6 | 80.3 | 87.8 |
8 | R maxillary sinus | Squamous cell carcinoma | T2N0M0 | 59.4 Gy/1.8 Gy | 31.3 | 63.3 | 31.0 | 11.0 | 51.0 | 1.1 |
9 | R nasal vestibule | Squamous cell carcinoma | T4aN0M0 | 73.2 Gy/2 Gy/1.2 Gy BID | 40.1 | 65.7 | 38.4 | 36.9 | 65 | 32.1 |
Listed as total dose/dose per fraction. BID: twice a day fractions.
Doses to the retina, as defined in the methods section.