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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Apoptosis. 2013 Sep;18(9):1071–1082. doi: 10.1007/s10495-013-0855-1

Fig. 9. Effects of caspase inhibitors on the cytotoxicity of PQ1.

Fig. 9

T47D cells were pre-treated with 20 μM caspase-3 inhibitor (Ac-DMQD-CHO), caspase-8 inhibitor (Ac-IETD-CHO), or caspase-9 inhibitor (Ac-LEHD-CHO) for 1 hour, and exposed to 500 nM PQ1 for 23 hours. Cells without treatments and cells treated with 500 nM PQ1 for 24 hours were used as controls. Cell viability was determined by trypan blue method. Data were obtained in three independent experiments and are represented as the mean ± S.D. * P-value is <0.05 compared to control. **P-value is <0.05 compared to treatment with 500 nM PQ1 for 24 hours.