Table 4.

All-cause mortality hazard ratio and 95% confidence intervals for serum phosphorus levels stratified by age category case-mix and MICS adjusted Cox proportional hazard models

Phosphorus (mg/dl)	15-<45 yo (N=19,182)		45-<65 yo (N=41,770)		65-<70 yo (N=12,562)		70-<75 yo (N=12,240)		≥75 yo (N=22,063)
	HR(95%CI)	P	HR(95%CI)	P	HR(95%CI)	P	HR(95%CI)	P	HR(95%CI)	P
<3.5	1.16 (0.95-1.42)	0.15	0.95 (0.87-1.04)	0.297	1.21 (1.07-1.37)	0.002	1.13 (1.02-1.25)	0.021	1.28 (1.2-1.37)	<0.001
3.5-5.5 (Reference)	1	N/A	1	N/A	1	N/A	1	N/A	1	N/A
>5.5-6.5	1.09 (1.01-1.17)	0.027	1.11 (1.07-1.15)	<0.001	1.11 (1.05-1.18)	<0.001	1.13 (1.07-1.19)	<0.001	1.16 (1.11-1.21)	<0.001
>6.5-7.5	1.26 (1.16-1.37)	<0.001	1.36 (1.3-1.42)	<0.001	1.49 (1.37-1.63)	<0.001	1.41 (1.29-1.54)	<0.001	1.34 (1.25-1.45)	<0.001
>7.5-8.5	1.44 (1.3-1.59)	<0.001	1.64 (1.54-1.75)	<0.001	1.66 (1.45-1.91)	<0.001	1.91 (1.63-2.24)	<0.001	1.73 (1.51-1.98)	<0.001
>8.5	1.94 (1.73-2.18)	<0.001	1.95 (1.77-2.14)	<0.001	2.22 (1.71-2.87)	<0.001	2.77 (2.1-3.66)	<0.001	1.56 (1.22-1.98)	<0.001

Note: Case-mix and MICS model includes adjustment for age, gender, race/ethnicity, presence of diabetes mellitus, baseline comorbid conditions, history of tobacco smoking, dialysis vintage categories, primary insurance, marital status, types of vascular access, dialysis dose as indicated by single pool Kt/V, residual renal function, body mass index, serum levels of albumin, intact parathyroid hormone, calcium, total-iron binding capacity, ferritin, creatinine, bicarbonate, hemoglobin, blood white blood cells, lymphocyte percentage and normalized protein nitrogen appearance.

Abbreviations: MICS, malnutrition-inflammation complex syndrome; HR, hazard ratio; CI, confidence interval.