Figure 2. Induction of CYP7A1 induces SREBP2 and miR-33a expression in Cyp7a1-tg mice.
Wild type and Cyp7a1-tg mice were fed a standard chow diet or Western diet for 4 months. The mRNA expression of (A) SREBP2 and (B) miR-33a was measured by real-time PCR. Results are expressed as mean ± S.E. “*” indicates p < 0.05 vs. WT of same diet, n=4.