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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Neurochem Res. 2013 May 29;38(9):1777–1784. doi: 10.1007/s11064-013-1080-6

Fig. 1.

Fig. 1

GMF up-regulation in the entorhinal cortex specifically at the sites of APs (A,B, C) and NFTs (D,E,F) in AD brain. Double immunohistochemistry depicting APs (with 6E10 antibody) in blue-gray color (s in A,B,C, arrow heads) and GMF-positive glial cells in brown color (arrows A,B,C) in the entorhinal cortex of AD brains. Note, GMF-positive astrocytes were localized near the 6E10-positive APs (C). Double immunostaining of GMF and Tau antibody showing the association of GMF (blue-gray color; arrows in F) and Tau-immunoreactive NFTs (brown color in D,E,F, arrow head) in the entorhinal cortex of AD brain. Note the double labeling of GMF immunoreactive glial cells and Tau-immunostained NFTs, and astrocytes present near to that exhibit GMF-positive staining (D,E,F).