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. Author manuscript; available in PMC: 2014 Jun 21.
Published in final edited form as: ACS Chem Biol. 2013 Mar 29;8(6):1232–1240. doi: 10.1021/cb400027q

Table 1.

Comparison between the chemical shift parameters (ΔωN) for the open/closed conformational exchange of EIC obtained by NMR relaxation dispersion experiments (14), and 15N chemical shift perturbations (ΔδN) induced by αKG on the NMR spectrum of EIC.

G337 K340 E341 L355 W357 R358 A359 I426 G427 R465 N467
|ΔωN| (ppm)a 2.0 0.6 1.0 1.1 1.0 0.7 2.0 1.9 2.0 0.8 0.8
ΔδN (ppm) 0.6 0.1 0.4 - 0.7 0.9 1.1 1.6 1.5 1.0 -
|(|ΔωN|-ΔδN)|/|ΔωN| 0.7 0.8 0.6 - 0.3 0.3 0.4 0.2 0.3 0.2 -
a

The error in the values of |ΔωN| is ±0.1 ppm with the exception of that for Leu355 and Arg465 which is ±0.2 ppm.