Figure 8.

Retention of training effects. Four weeks after training ended (35 dpi), motor control was assessed using gridwalk and treadmill kinematics. ETT in KO mice resulted in near-normal measures of trunk displacement (A), toe dragging (B), time spent in swing/stance (C,D), and peak velocity of the ankle during swing (E). Trained WT and unexercised controls displayed significant motor deficits compared with naive in almost all kinematic measures (p < 0.05). ETT resulted in significantly worse rung-rung paw placement on gridwalk in WT mice (F, p < 0.05). n = 6–10/group. *Significantly different from naive for A–E, *Significantly different from KO ETT for F.