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. 2013 Aug 7;33(32):13101–13111. doi: 10.1523/JNEUROSCI.1576-13.2013

Table 2.

Late training is ineffective in KO and WT mice

Naive (n = 10) KO Pre (n = 6) KO Post (n = 6) WT Pre (n = 5) WT Post (n = 5)
BMS 9 5.7 ± 0.4 5.6 ± 0.2 4.8 ± 0.2 5.0 ± 0.3
Trunk displacement (cm) 0.54 ± 0.04 1.01 ± 0.31 0.64 ± 0.11 1.24 ± 0.40 0.87 ± 0.26
Toe dragging (s) 0.031 ± 0.001 0.067 ± 0.010 0.051 ± 0.004 0.077 ± 0.013 0.078 ± 0.007
Swing time (s) 0.113 ± 0.005 0.060 ± 0.012 0.078 ± 0.005 0.055 ± 0.023 0.068 ± 0.019
Stance time (s) 0.30 ± 0.01 0.69 ± 0.09 0.52 ± 0.04 0.82 ± 0.14 0.91 ± 0.09
Peak ankle velocity (cm/s) 22.9 ± 1.5 15.5 ± 3.3 19.3 ± 1.6 11.4 ± 4.7 12.3 ± 3.7
Peak toe velocity (cm/s) 30.0 ± 1.8 21.8 ± 4.7 27.7 ± 2.0 16.4 ± 6.8 19.6 ± 5.5
Gridwalk (% success) 84.3 ± 1.7 12.3 ± 3.2 11.3 ± 3.1 13.1 ± 1.2 14.6 ± 3.0

Recovery was examined before (35 d) and after (42 dpi) LTT in KO and WT mice using a battery of locomotor tests. Open field (BMS), gridwalk, and kinematic measures revealed no improvements or deficits that resulted from training in KO and WT groups. Data are shown as means ± SEM.