TABLE 3.
Logistic regression model of factors associated with clinical outcomes in children successfully recovered from MAM1
Independent variable | OR [95% CI] | P value |
Success2 at 3 mo | ||
Female child | 1.64 [1.27, 2.11] | <0.001 |
Reported to have good appetite on enrollment | 2.91 [1.02, 8.29] | 0.045 |
WHZ at enrollment | 2.67 [2.07, 3.45] | <0.001 |
HFIAS score | 1.03 [1.01, 1.05] | 0.019 |
Caretaker is mother | 3.06 [1.54, 6.11] | 0.001 |
Mother alive | 3.11 [1.80, 5.37] | <0.001 |
Child without HIV infection | 1.96 [1.21, 3.19] | 0.006 |
Success at 12 mo | ||
Female child | 2.35 [1.88, 2.94] | <0.001 |
WHZ at enrollment | 3.90 [3.09, 4.91] | <0.001 |
HAZ at enrollment | 1.08 [1.01, 1.16] | 0.046 |
HFIAS score | 1.02 [1.01, 1.04] | 0.008 |
Mother alive | 3.11 [1.80, 5.37] | <0.001 |
Child without HIV infection | 2.60 [1.62, 4.18] | <0.001 |
Developed SAM by 3 mo | ||
MUAC at enrollment | 0.71 [0.65, 0.77] | <0.001 |
WHZ at enrollment | 0.25 [0.16, 0.40] | <0.001 |
Child without HIV infection | 0.39 [0.18, 0.84] | 0.002 |
Developed SAM by 12 mo | ||
Female gender | 0.58 [0.40, 0.84] | 0.004 |
MUAC at enrollment | 0.82 [0.76, 0.89] | <0.001 |
WHZ at enrollment | 0.41 [0.29, 0.59] | <0.001 |
HAZ at enrollment | 0.87 [0.78, 0.98] | 0.026 |
Child without HIV infection | 0.37 [0.20, 0.70] | 0.002 |
Age (in months) | 0.97 [0.95, 0.98] | 0.001 |
Died by 3 mo | ||
MUAC at enrollment | 0.66 [0.62, 0.72] | <0.001 |
Having a father who died | 8.19 [2.29, 29.4] | 0.001 |
Died by 12 mo | ||
MUAC at enrollment | 0.78 [0.72, 0.85] | 0.004 |
HAZ at enrollment | 0.83 [0.71, 0.98] | 0.032 |
Having a father who died | 3.21 [1.20, 8.59] | 0.020 |
Child without HIV infection | 0.43 [0.19, 0.99] | 0.046 |
Logistic regression with stepwise backward exclusion of independent variables. Cox and Snell 2 for successful recovery: R2 = 0.30 for 3 mo, R2 = 0.10 for 12 mo; for development of SAM, R2 = 0.63 for 3 mo, R2 = 0.55 for 12 mo; for death, R2 = 0.71 for 3 mo, R2 = 0.66 for 12 mo. HAZ, height-for-age Z-score; HFIAS, Household Food Insecurity Access Scale; MAM, moderate acute malnutrition; MUAC, mid-upper arm circumference; WHZ, weight-for-height Z-score.
Success is defined as surviving with WHZ ≥−2 or MUAC ≥12.5 cm without developing edema.