Fig. 1.

Cholesterol absorption rates in various inbred strains of mice following olive oil gavage. Nonfasted female mice were gavaged with 2 μCi [³H]cholesterol in 200 μl olive oil. A, C: Plasma samples were collected over the course of 7 h, and plasma radiolabel was measured by liquid scintillation counting. B: Plasma samples (7 h) were separated on a 3–20% NaBr gradient and fractionated, and [³H]cholesterol levels in each fraction were determined by liquid scintillation counting. C: Comparison of additional inbred mouse strains. Reported plasma HDL cholesterol levels for females of each strain are shown in parenthesis for comparison (26). Data represent mean ± standard deviation of triplicate mice.