TABLE 6.
Cytokine Family | Number of Genes | Number of Genes Upregulated in RAW264.7 Cells |
Number of Genes Upregulated in TGEM Cells |
||||||||||||
0.5 h | 1 h | 2 h | 4 h | 8 h | 12 h | 24 h | 0.5 h | 1 h | 2 h | 4 h | 8 h | 12 h | 24 h | ||
Chemokines | 34 | 2 | 7 | 10 | 16 | 12 | 11 | 12 | 4 | 11 | 13 | 16 | 17 | 17 | 17 |
Class I cytokines (hematopoietin family) | 27 | 0 | 2 | 4 | 5 | 4 | 4 | 4 | 0 | 6 | 7 | 4 | 5 | 5 | 5 |
Class II cytokines (interferon/IL-10 family) | 11 | 0 | 2 | 3 | 2 | 3 | 2 | 1 | 1 | 3 | 4 | 4 | 3 | 4 | 4 |
IL-1 family | 9 | 1 | 2 | 3 | 4 | 5 | 5 | 5 | 2 | 3 | 4 | 4 | 4 | 4 | 4 |
IL-17 family | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
PDGF family | 25 | 0 | 0 | 2 | 3 | 2 | 1 | 3 | 0 | 0 | 2 | 2 | 2 | 2 | 1 |
TGF-β family | 22 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
TNF family | 17 | 2 | 2 | 3 | 4 | 3 | 1 | 2 | 2 | 3 | 5 | 7 | 6 | 5 | 5 |