Table 1.
Parameter | Low collateralization group (n=186) | High collateralization group (n=292) | P value |
Age (year) | 66±10 | 64±11 | 0.07 |
Age ≥65 years | 102 (55.7%) | 136 (46.1%) | 0.04 |
Male | 130 (71%) | 233 (79%) | 0.048 |
Cardiovascular risk factors | |||
Smoking | 69 (37.1%) | 113 (38.3%) | 0.72 |
Hypertension | 115 (61.8%) | 209 (71.6%) | 0.026 |
Hyperlipidemia | 107 (57.5%) | 112 (38.4%) | <0.001 |
Diabetes mellitus | 83 (45.4%) | 75 (25.4%) | <0.001 |
Systolic blood pressure (mmHg) | 136±17 | 140±16 | 0.008 |
Diastolic blood pressure (mmHg) | 82±10 | 85±8 | 0.001 |
Triglyceride (mmol/L) | 1.91±1.19 | 1.79±0.99 | 0.06 |
Total cholesterol (mmol/L) | 4.37±1.43 | 4.14±1.12 | 0.05 |
HDL-C (mmol/L) | 0.98±0.25 | 1.05±0.26 | 0.02 |
LDL-C (mmol/L) | 2.69±1.40 | 2.57±0.89 | 0.20 |
Apoprotein-A (g/L) | 1.22±0.25 | 1.19±0.23 | 0.45 |
Apoprotein-B (g/L) | 1.00±0.33 | 0.88±0.27 | 0.009 |
Lipoprotein (a) (g/L) | 0.24±0.19 | 0.24±0.21 | 0.57 |
Fasting glucose (mmol/L) | 6.02±1.97 | 5.39±1.39 | <0.001 |
HbA1c (%) | 6.44±1.10 | 6.19±1.11 | <0.001 |
BUN (mmol/L) | 5.50±1.95 | 5.07±1.65 | 0.001 |
Creatinin (μmol/L) | 82.8±19.8 | 80.8±27.3 | 0.003 |
Uric acid (μmol/L) | 339±80 | 328±79 | 0.15 |
eGFR<60 ml/(min∙1.73 m2) | 48 (26.2%) | 36 (12.2%) | <0.001 |
High-sensitivity CRP (mg/L) | 5.85±3.01 | 5.28±2.71 | 0.03 |
Medications | |||
Oral antiplatelet | 168 (100%) | 292 (100%) | 1.00 |
ACEI | 79 (42.5%) | 138 (47.3%) | 0.30 |
β-blockers | 86 (46.2%) | 121 (41.4%) | 0.31 |
Nitrates | 48 (25.8%) | 72 (25.7%) | 0.77 |
Calcium antagonists | 23 (28.4%) | 15 (25.0%) | 0.653 |
Statins | 175 (94.1%) | 285 (97.6%) | 0.89 |
Number of significant CAD | 0.004 | ||
1-vessel disease | 51 (27.9%) | 58 (19.7%) | |
2-vessel disease | 53 (29.0%) | 129 (43.7%) | |
3-vessel disease | 79 (43.2%) | 108 (36.6%) |
Values are expressed as mean±SD or number of patients (percentage). Chi-square for categorical variables. HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; HbA1c: glycosylated hemoglobin; BUN: blood urea nitrogen; eGFR: estimated glomerular filtration rate; CRP: C-reactive protein; ACEI: angiotensin-converting enzyme inhibitor; CAD: coronary artery disease