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Antibody titers in subjects with preexisting high specific binding anti-VWF antibodies
| Subject | Gender | Age, y | Binding anti-VWF Ab titer | ||
|---|---|---|---|---|---|
| Screening | Preinfusion 2 | Study termination | |||
| 21 | F | 23 | 1:1280 | 1:5120* | 1:5120 |
| 23 | M | 19 | 1:1280 | NA† | 1:2560 |
Postinfusion with pdVWF-pdFVII and preinfusion with rVWF-rFVIII.
Subject 23 received only rVWF-rFVIII (not enrolled in the crossover cohort).
