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. Author manuscript; available in PMC: 2013 Aug 7.
Published in final edited form as: Sci Transl Med. 2011 Jul 20;3(92):92ra65. doi: 10.1126/scitranslmed.3002289

Table 4.

Relative probability (HR, hazard ratio) of birth per month by husband’s DEFB126 genotype in prospective cohort study.

Husband DEFB126 n Live birth
n (%)
Mean (SD)
time to live
birth or end
of follow-up
in months
HR (95% CI) 2-sided P
Additive model
  WT/WT 145 106 (73%) 15.4 (7.4) Referent
  WT/Del 235 165 (70%) 15.8 (7.4) 0.9 (0.7, 1.2) 0.581
  Del/Del 100 60 (60%) 17.4 (7.4) 0.7 (0.5, 1.0) 0.026
Recessive model
  WT/WT and WT/Del 380 271 (71%) 15.7 (7.3) Referent
  Del / Del 100 60 (60%) 17.4 (7.4) 0.7 (0.5, 1.0) 0.026