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. Author manuscript; available in PMC: 2014 Jul 19.
Published in final edited form as: Science. 2013 Jul 19;341(6143):295–298. doi: 10.1126/science.1235872

Fig. 3. Dietary protein blocks the inactivation of digoxin.

Fig. 3

Serum (A) and urinary (B) digoxin levels from the type strain experiment. Fecal digoxin levels showed a consistent trend: the mean area under the curve was 6.226 ng digoxin*h/mL in germ-free mice, 3.576 for mice on the 0% protein diet, and 6.364 for mice on the 20% protein diet. Serum (C) and urinary (D) digoxin levels from each group. Digoxin levels were quantified by ELISA (7). Values are the mean±sem. Asterisks indicate statistical significance by Student’s t test (*=P<0.05; **=P<0.01). n=4–5 mice/group. NS=not significant.