Table 2.

Reasons for HCV Treatment Ineligibility Among All Patients According to Race

	Black* (n = 962)	Nonblack* (n = 3507)	Relative Risk (95% CI)	P†
Failed screening evaluation	387 (40)	999 (28)	1.41 (1.29–1.55)	<0.001
HCV treatment not initiated for reason other than treatment ineligibility	103 (11)	245 (7)	1.53 (1.23–1.91)	<0.001
Did not wish to continue	55 (6)	160 (5)	1.25 (0.93–1.69)	0.14
Lost to follow-up	39 (4)	53 (2)	2.68 (1.79–4.03)	<0.001
Noncompliance	7 (1)	31 (1)	0.82 (0.36–1.86)	0.64
Adverse event	2 (<1)	1 (<1)	n/a‡	N/a‡
HCV treatment ineligible§	284 (30)	754 (21)	1.37 (1.22–1.54)	<0.001
Abnormal hematologic value	65 (7)	83 (2)	2.85 (2.08–3.92)	<0.001
Abnormal chemistry value	60 (6)	78 (2)	2.80 (2.02–3.90)	<0.001
Poorly controlled diabetes mellitus	14 (1)	15 (0.4)	3.40 (1.65–7.02)	<0.001
Clinically significant cardiac disease	5 (0.5)	13 (0.4)	1.40 (0.50–3.92)	0.52
Preexisting or uncontrolled medical disease‖	74 (8)	196 (6)	1.38 (1.06–1.78)	0.02
Preexisting or uncontrolled psychiatric disease¶	41 (4)	125 (4)	1.20 (0.85–1.69)	0.31
Recent drug or alcohol abuse	19 (2)	101 (3)	0.69 (0.42–1.11)	0.12
Exclusionary virology including HCV RNA not detected, non-1 HCV genotype and missing	14 (1)	159 (5)	0.32 (0.19–0.55)	<0.001
HCV treatment ineligible for reason other than exclusionary virology	270 (28)	595 (17)	1.65 (1.46–1.87)	<0.001

Abbreviations: CI, confidence interval; HCV, hepatitis C virus; RNA, ribonucleic acid.

^*Data shown are number (percentage of total number).

^†P values were not adjusted for multiplicity.

^‡Chi-square calculation not performed due to small sample size.

^§Patients may have more than 1 reason for ineligibility.

^‖Identified by the investigator at the time of screening; no further information describing the specific preexisting or uncontrolled medical condition(s) was available.

^¶Clinical diagnosis or Center for Epidemiologic Studies Depression Scale score >25.