Table 2. Genotype And allele Frequencies Of Obesity-Associated Polymorphisms In Patients With And Without The Metabolic Syndrome As Determined By The NCEP ATP III Definition.

Genotype/allelotype	NCEP (yes) n (%)	NCEP (no) n (%)	OR (95% CI)	p-value
Adiponectin 45 T→G
TT	208 (71)	134 (71)	1.00 (0.66–1.53)	1.000
TG	81 (27)	50 (26)	0.94 (0.61–1.45)	0.834
GG	6 (2)	6 (3)	1.57 (0.41–5.96)	0.552
T allele	497 (84)	318 (84)	0.96 (0.67–1.39)	0.858
G allele	93 (16)	62 (16)	1.04 (0.72–1.50)	0.858
Adiponectin 276 G→T
GG	181 (61)	113 (59)	0.92 (0.63–1.37)	0.704
GT	99 (34)	65 (34)	1.03 (0.69–1.54)	0.922
TT	15 (5)	12 (6)	1.26 (0.53–2.95)	0.551
G allele	461 (78)	291 (77)	0.92 (0.67–1.26)	0.582
T allele	129 (22)	89 (23)	1.09 (0.79–1.50)	0.582
LEPR K109R
AA	220 (75)	130 (68)	0.74 (0.48–1.13)	0.147
AG	69 (23)	56 (29)	1.37 (0.89–2.11)	0.138
GG	6 (2)	4 (2)	1.04 (0.21–4.43)	1.000
A allele	509 (86)	316 (83)	0.79 (0.54–1.14)	0.197
G allele	81 (14)	64 (17)	1.27 (0.88–1.85)	0.197
LEPR Q223R
TT	59 (20)	30 (16)	0.76 (0.45–1.26)	0.280
TC	140 (48)	93 (49)	1.08 (0.73–1.58)	0.709
CC	95 (32)	65 (35)	1.11 (0.74–1.66)	0.621
T allele	258 (44)	153 (40)	0.88 (0.67–1.15)	0.350
C allele	330 (56)	223 (59)	1.14 (0.87–1.50)	0.350
MC4R (rs17882313)
CC	38 (13)	23 (12)	0.93 (0.51–1.67)	0.889
TC	127 (43)	76 (40)	0.88 (0.60–1.30)	0.511
TT	130 (44)	91 (48)	1.17 (0.80–1.71)	0.455
C allele	203 (34)	122 (32)	0.90 (0.68–1.20)	0.486
T allele	386 (66)	258 (68)	1.11 (0.84–1.48)	0.486
FTO (rs9939609)
AA	32 (11)	21(11)	1.02 (0.54–1.90)	1.000
AT	125 (42)	84 (44)	1.08 (0.73–1.58)	0.708
TT	138 (47)	85 (45)	0.92 (0.63–1.35)	0.709
A allele	189 (32)	126 (33)	1.05 (0.79–1.40)	0.726
T allele	401 (68)	254 (67)	0.95 (0.72–1.26)	0.726

NCEP: National Cholesterol Education Program, LEPR: leptin receptor, OR: odd ratio, CI: confidence interval, MC4R: melanocortin-4-receptor, FTO: fat mass and obesity associated.