Table 1.

Yields of fellutamide B (2) and deoxy-fellutamides B, C, and D (6–8) after cleavage from resin based on the original loading of the Weinreb amide resin (6 steps).

Compound	R1	R3	R4	Yield (%)
Fellutamide B (2)	C9H19	CH2CH(CH3)2	OH	55
Deoxyfellutamide B (6)	C9H19	CH2CH(CH3)2	H	44 (24% after purification)
Deoxyfellutamide C (7)	C11H23	CH(CH3)2	OH	53
Deoxyfellutamide D (8)	C11H23	CH2CH(CH3)2	OH	60