Figure 3. NF-κB time course behaviour of A. Concentrations of nuclear NF-κB over time, simulated using the in silico model described here, B. Concentrations of nuclear NF-κB over time, simulated using the in silico model described by Covert et al., C. Experimental data from LPS-treated mouse embryo fibroblasts as described by Covert et al. [22].

C is reprinted from Covert, M. W., Leung, T. H., Gaston, J. E., & Baltimore, D. (2005). Achieving stability of lipopolysaccharide-induced NF-kappaB activation. Science (New York, N.Y.), 309(5742), 1854-7. under a CC BY license, with permission from AAAS, original copyright 2005.