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. 2013 Jul 30;8(7):e70180. doi: 10.1371/journal.pone.0070180

Figure 5. NF-κB time course behaviour in TRIF and MyD88 knock-out conditions.

Figure 5

A. Concentrations of nuclear NF-κB over time, simulated using TRIF and MyD88 knock-out versions of the in silico model described here, B. Concentrations of nuclear NF-κB over time, simulated using TRIF and MyD88 knock-out versions of the in silico model described by Covert et al., C. Experimental in vitro data from LPS-treated TRIF or MyD88 knock-out mouse embryo fibroblasts as described by Covert et al. [22]. B and C are reprinted from Covert, M. W., Leung, T. H., Gaston, J. E., & Baltimore, D. (2005). Achieving stability of lipopolysaccharide-induced NF-kappaB activation. Science (New York, N.Y.), 309(5742), 1854-7. under a CC BY license, with permission from AAAS, original copyright 2005.