Table 5. Proportion of variance explained by clinical characteristics, common variants, and LF/rare variants in IRASFS Hispanic and African American cohorts.
Contributors to variance | N | Proportion of Variation Explained | N | Proportion of Variation Explained | p-value | |
---|---|---|---|---|---|---|
Hispanics | None | 1151 | -- | 628 | -- | -- |
Clinical Characteristics | 820 | 0.31 | 628 | 0.32 | 1.16E-47 | |
Rare SNPs | 1104 | 0.18 | 628 | 0.16 | 6.40E-15 | |
Common SNPs | 890 | 0.050 | 628 | 0.069 | 0.194 | |
All SNPs | 880 | 0.23 | 628 | 0.21 | 1.16E-09 | |
Clinical + Rare SNPs | 785 | 0.44 | 628 | 0.44 | 5.39E-66 | |
Clinical + Common SNPs | 637 | 0.38 | 628 | 0.38 | 3.13E-40 | |
Clinical + All SNPs | 628 | 0.49 | 628 | 0.49 | 1.33E-56 | |
African Americans | None | 574 | -- | 360 | -- | -- |
Clinical Characteristics | 437 | 0.44 | 360 | 0.47 | 5.82E-20 | |
Rare SNPs | 494 | 0.057 | 360 | 0.063 | 5.44E-12 | |
Common SNPs | 479 | 0.085 | 360 | 0.081 | 1.44E-10 | |
All SNPs | 477 | 0.14 | 360 | 0.15 | 4.68E-09 | |
Clinical + Rare SNPs | 374 | 0.50 | 360 | 0.51 | 7.77E-18 | |
Clinical + Common SNPs | 362 | 0.54 | 360 | 0.54 | 6.87E-16 | |
Clinical + All SNPs | 360 | 0.59 | 360 | 0.59 | 4.48E-13 |