Table 5. Proportion of variance explained by clinical characteristics, common variants, and LF/rare variants in IRASFS Hispanic and African American cohorts.
For each population, the contributors to the variance delineated with the number of observations, proportion of variance explained for the full cohort or limited to individuals with complete data for all contributors and the corresponding p-value.
| Contributors to variance | N | Proportion of Variation Explained | N | Proportion of Variation Explained | p-value | |
|---|---|---|---|---|---|---|
| Hispanics | None | 1151 | -- | 628 | -- | -- |
| Clinical Characteristics | 820 | 0.31 | 628 | 0.32 | 1.16E-47 | |
| Rare SNPs | 1104 | 0.18 | 628 | 0.16 | 6.40E-15 | |
| Common SNPs | 890 | 0.050 | 628 | 0.069 | 0.194 | |
| All SNPs | 880 | 0.23 | 628 | 0.21 | 1.16E-09 | |
| Clinical + Rare SNPs | 785 | 0.44 | 628 | 0.44 | 5.39E-66 | |
| Clinical + Common SNPs | 637 | 0.38 | 628 | 0.38 | 3.13E-40 | |
| Clinical + All SNPs | 628 | 0.49 | 628 | 0.49 | 1.33E-56 | |
| African Americans | None | 574 | -- | 360 | -- | -- |
| Clinical Characteristics | 437 | 0.44 | 360 | 0.47 | 5.82E-20 | |
| Rare SNPs | 494 | 0.057 | 360 | 0.063 | 5.44E-12 | |
| Common SNPs | 479 | 0.085 | 360 | 0.081 | 1.44E-10 | |
| All SNPs | 477 | 0.14 | 360 | 0.15 | 4.68E-09 | |
| Clinical + Rare SNPs | 374 | 0.50 | 360 | 0.51 | 7.77E-18 | |
| Clinical + Common SNPs | 362 | 0.54 | 360 | 0.54 | 6.87E-16 | |
| Clinical + All SNPs | 360 | 0.59 | 360 | 0.59 | 4.48E-13 | |