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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Genet Epidemiol. 2012 Oct 2;37(1):13–24. doi: 10.1002/gepi.21685

Table 5. Proportion of variance explained by clinical characteristics, common variants, and LF/rare variants in IRASFS Hispanic and African American cohorts.

For each population, the contributors to the variance delineated with the number of observations, proportion of variance explained for the full cohort or limited to individuals with complete data for all contributors and the corresponding p-value.

Contributors to variance N Proportion of Variation Explained N Proportion of Variation Explained p-value
Hispanics None 1151 -- 628 -- --
Clinical Characteristics 820 0.31 628 0.32 1.16E-47
Rare SNPs 1104 0.18 628 0.16 6.40E-15
Common SNPs 890 0.050 628 0.069 0.194
All SNPs 880 0.23 628 0.21 1.16E-09
Clinical + Rare SNPs 785 0.44 628 0.44 5.39E-66
Clinical + Common SNPs 637 0.38 628 0.38 3.13E-40
Clinical + All SNPs 628 0.49 628 0.49 1.33E-56

African Americans None 574 -- 360 -- --
Clinical Characteristics 437 0.44 360 0.47 5.82E-20
Rare SNPs 494 0.057 360 0.063 5.44E-12
Common SNPs 479 0.085 360 0.081 1.44E-10
All SNPs 477 0.14 360 0.15 4.68E-09
Clinical + Rare SNPs 374 0.50 360 0.51 7.77E-18
Clinical + Common SNPs 362 0.54 360 0.54 6.87E-16
Clinical + All SNPs 360 0.59 360 0.59 4.48E-13