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. 2013 Jul 11;24(8):1250–1261. doi: 10.1681/ASN.2012121216

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Copyright © 2013 by the American Society of Nephrology

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Figure 5. — SS-31 promotes restoration of brush border in proximal tubular cells after reperfusion. Representative electron microscopic images of proximal tubules brush border from (A) sham-operated control, (B) saline-treated animal after 30 minutes of ischemia, (C) saline-treated animal after 30 minutes of ischemia and 5 minutes of reperfusion, and (D) SS-31–treated animal after 30 minutes of ischemia and 5 minutes of reperfusion. (E) Actin filaments (shown by arrows) are seen here in higher magnification from the area selected in D. (F) F-actin staining in proximal tubules of (top panel) saline and (bottom panel) SS-31 kidneys (a) at the end of 30 minutes of ischemia and after (b) 5 minutes of reperfusion and (c) 20 minutes of reperfusion. Original magnification, ×600.