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. Author manuscript; available in PMC: 2013 Aug 7.
Published in final edited form as: Adv Exp Med Biol. 2010;661:419–434. doi: 10.1007/978-1-60761-500-2_27

Table 27.1.

PubMatrix evaluation of selected sorafenib-driven genes across PH-related search terms

Gene name Gene symbol Ontology PH Proliferation Hypoxia Vascular remodeling Angiogenesis Cancer
Actin γ2 Actg2 Muscle 3 131 3 7 12 180
Tropomyosin 3, γ Tpm3 Muscle 0 7 1 0 1 33
Complement component 1, q subcomponent, γ polypeptide C1qg Defense and immune 0 0 0 0 0 1
RT1 class1, CE12 Rt1-CE12 Defense and immune 0 0 0 0 0 0
Caldesmon 1 Cald1 Cell proliferation 1 73 7 7 9 212
V-maf musculoaponeurotic fibrosarcoma oncogene homolog Maf Cell proliferation 0 95 4 0 8 278
TGF-β3 Tgfb3 Cell differentiation 61 3,463 133 129 371 3,173
Protein tyrosine phosphatase, receptor type R Ptprr Cell differentiation 0 13 0 0 2 22
3-Hydroxy-3-methylglutaryl-coenzyme A synthase 1 Hmgcs1 Metabolism 7 28 8 6 13 32
Isopentenyl-diphosphate δ isomerase Idi1 Metabolism 0 3 0 0 0 6