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Delivery of dsLNA probes to cells. Transfection efficiency with (a) different transfection reagents and (b) different amounts of Lipofectamine 2000 per 1.0 µg dsLNA probe. (c) Photothermal delivery of dsLNA probes targeting β-actin mRNA and random sequence to HeLa cells. Scale bars, 100 µm. (d) Normalized fluorescence intensities of dsLNA probes in the cytoplasm delivered by photothermal nanoblade.
