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. Author manuscript; available in PMC: 2013 Aug 7.
Published in final edited form as: J Trauma Acute Care Surg. 2013 Mar;74(3):756–765. doi: 10.1097/TA.0b013e3182826d7e

TABLE 3.

Trends in R Time (p = 0.10), Clot Strength (G) (p = 0.64), Fibrinogen (p = 0.58), and Platelet Count (p = 0.39), Expressed as Mean ± SEM, as well the Pearson Correlation Statistics of Fibrinogen and Platelet Count With Clot Strength During the 5-day Study Period

Day 1 Day 2 Day 3 Day 4 Day 5
Control (n)
  R time, min 5.32 ± 0.32 6.08 ± 0.52 4.96 ± 0.21 4.70 ± 0.29 5.03 ± 0.26
  G, dynes/cm2 10.26 ± 0.76 11.29 ± 0.76 12.25 ± 0.91 13.83 ± 0.85 14.72 ± 0.87
  Fibrinogen, mg/dL 636 ± 137 671 ± 117 715 ± 120 716 ± 159 691 ± 147
  Platelets, 1,000/µL 139 ± 49 154 ± 83 183 ± 135 216 ± 185 262 ± 172
Correlation coefficients (R, 95% CI)
  Fibrinogen and G R (95% CI) 0.68 (0.14–0.91) 0.63 (0.28–0.84) 0.25 (−0.24 to 0.64) 0.55 (0.11–0.81) 0.45 (0.01 to 0.75)
  p 0.0142 0.0012 0.3004 0.0144 0.0395
  Platelets and G R (95% CI) 0.56 (0.20–0.79) 0.44 (0.04–0.71) 0.76 (0.50 to 0.89) 0.69 (0.33–0.88) 0.57 (0.19 to 0.81)
  p 0.0037 0.0282 <0.0001 0.0007 0.0045
TEG-guided (n = 25)
  R time, min 5.26 ± 0.31 5.75 ± 0.34 4.98 ± 0.23 5.31 ± 0.43 5.68 ± 0.55
  G, dynes/cm2 9.36 ± 0.49 10.47 ± 0.48 12.35 ± 0.64 14.16 ± 0.85 14.17 ± 0.74
  Fibrinogen, mg/dL 563 ± 102 610 ± 136 624 ± 154 652 ± 161 687 ± 158
Platelets, 1,000/µL 120 ± 41 128 ± 35 148 ± 54 199 ± 75 268 ± 83
Correlation coefficients (R, 95% CI)
  Fibrinogen and G R (95% CI) 0.56 (0.04–0.84) 0.73 (0.44–0.88) 0.66 (0.34 to 0.84) 0.50 (0.07–0.77) 0.36 (−0.13 to 0.71)
  p 0.0306 <0.0001 0.0003 0.0202 0.1385
  Platelets and G R (95% CI) 0.55(0.19–0.78) 0.45 (0.05–0.73) 0.67 (0.35 to 0.85) 0.56 (0.14–0.81) 0.55(0.11 to 0.81)
  p 0.0036 0.025 0.0003 0.0098 0.0147