TABLE 3.
Trends in R Time (p = 0.10), Clot Strength (G) (p = 0.64), Fibrinogen (p = 0.58), and Platelet Count (p = 0.39), Expressed as Mean ± SEM, as well the Pearson Correlation Statistics of Fibrinogen and Platelet Count With Clot Strength During the 5-day Study Period
Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | |
---|---|---|---|---|---|
Control (n) | |||||
R time, min | 5.32 ± 0.32 | 6.08 ± 0.52 | 4.96 ± 0.21 | 4.70 ± 0.29 | 5.03 ± 0.26 |
G, dynes/cm2 | 10.26 ± 0.76 | 11.29 ± 0.76 | 12.25 ± 0.91 | 13.83 ± 0.85 | 14.72 ± 0.87 |
Fibrinogen, mg/dL | 636 ± 137 | 671 ± 117 | 715 ± 120 | 716 ± 159 | 691 ± 147 |
Platelets, 1,000/µL | 139 ± 49 | 154 ± 83 | 183 ± 135 | 216 ± 185 | 262 ± 172 |
Correlation coefficients (R, 95% CI) | |||||
Fibrinogen and G R (95% CI) | 0.68 (0.14–0.91) | 0.63 (0.28–0.84) | 0.25 (−0.24 to 0.64) | 0.55 (0.11–0.81) | 0.45 (0.01 to 0.75) |
p | 0.0142 | 0.0012 | 0.3004 | 0.0144 | 0.0395 |
Platelets and G R (95% CI) | 0.56 (0.20–0.79) | 0.44 (0.04–0.71) | 0.76 (0.50 to 0.89) | 0.69 (0.33–0.88) | 0.57 (0.19 to 0.81) |
p | 0.0037 | 0.0282 | <0.0001 | 0.0007 | 0.0045 |
TEG-guided (n = 25) | |||||
R time, min | 5.26 ± 0.31 | 5.75 ± 0.34 | 4.98 ± 0.23 | 5.31 ± 0.43 | 5.68 ± 0.55 |
G, dynes/cm2 | 9.36 ± 0.49 | 10.47 ± 0.48 | 12.35 ± 0.64 | 14.16 ± 0.85 | 14.17 ± 0.74 |
Fibrinogen, mg/dL | 563 ± 102 | 610 ± 136 | 624 ± 154 | 652 ± 161 | 687 ± 158 |
Platelets, 1,000/µL | 120 ± 41 | 128 ± 35 | 148 ± 54 | 199 ± 75 | 268 ± 83 |
Correlation coefficients (R, 95% CI) | |||||
Fibrinogen and G R (95% CI) | 0.56 (0.04–0.84) | 0.73 (0.44–0.88) | 0.66 (0.34 to 0.84) | 0.50 (0.07–0.77) | 0.36 (−0.13 to 0.71) |
p | 0.0306 | <0.0001 | 0.0003 | 0.0202 | 0.1385 |
Platelets and G R (95% CI) | 0.55(0.19–0.78) | 0.45 (0.05–0.73) | 0.67 (0.35 to 0.85) | 0.56 (0.14–0.81) | 0.55(0.11 to 0.81) |
p | 0.0036 | 0.025 | 0.0003 | 0.0098 | 0.0147 |