Skip to main content
. Author manuscript; available in PMC: 2014 Mar 29.
Published in final edited form as: Circ Res. 2013 Feb 18;112(7):992–1003. doi: 10.1161/CIRCRESAHA.112.300749

Figure 8. Metabolic parameters and protein nitrosylation/nitration following NAC treatment.

Figure 8

Intraperitoneal glucose tolerance tests and (B) area under the curve (AUC) of 18-week-old WTD-fed Ldlr−/− and Ldlr−/−: MYFKO mice treated with Vehicle (V) or N-acetyl-cysteine (N) for 12 weeks after an 18-hr fast (n=6–9). Serum (C) glucose and (D) insulin levels in 20-week-old mice fed WTD and fasted for 16 hr (n=6–9). (E) Representative immunoblots and quantification of (F) Cys-SNO and (G) 3-NT in liver from 20-week-old mice after 14 weeks on WTD and treatment with Vehicle (V) or N-acetyl-L-cysteine (N) (n=3–4). SE: short exposure, LE: long exposure. *, # p < 0.05 vs. vehicle-treated Ldlr−/−, or Ldlr−/−: MYFKO mice, respectively.