Table 2.

SNPs with P < 0.05 in the African-American and European-American samples

SNPs	Gene (see Figure 2 and 3)	Allele	Allele frequency			Informative family			p-value (Z)
			AA	EA	AA and EA	AA	EA	AA and EA	AA	EA	AA and EA
rs2092786	RBM9	A	0.51	0.85	0.70	31	18	49	0.076 (−1.77)	0.14 (−1.48)	0.021 (−2.31)
		T	0.49	0.15	0.30				0.076 (1.77)	0.14 (1.48)	0.021 (2.31)
rs16996261	out of gene region	G	0.51	0.14	0.30	30	17	47	0.23 (1.21)	0.058 (1.90)	0.037 (2.09)
		T	0.49	0.86	0.70				0.23 (−1.21)	0.058 (−1.90)	0.037 (−2.09)
rs5995197	out of gene region	A	0.63	0.27	0.43	27	31	58	0.19 (1.31)	0.088 (1.71)	0.031 (2.15)
		T	0.34	0.73	0.57				0.19 (−1.31)	0.088 (−1.71)	0.031 (−2.15)
rs132736	APOL4	C	0.60	0.41	0.49	27	36	63	0.012 (−2.51)	0.63 (0.49)	0.049 (−1.97)
		T	0.40	0.59	0.51				0.012 (2.51)	0.63 (0.49)	0.049 (1.97)
rs9610449	APOL4/APOL2	C	0.22	0.34	0.29	22	31	53	0.0029 (2.98)	0.33 (0.98)	0.011 (2.56)
		T	0.78	0.66	0.71				0.0029 (−2.98)	0.33 (−0.98)	0.011 (−2.56)
rs6000200	APOL4/APOL2	C	0.71	0.66	0.71	21	31	52	0.00060 (−3.43)	0.33 (−0.98)	0.0052 (−2.79)
		G	0.29	0.34	0.29				0.00060 (3.43)	0.33 (0.98)	0.0052 (2.79)
rs2016988	APOL4/APOL2	C	0.38	0.07	0.21	31	12	43	0.016 (−2.40)	0.83 (−0.22)	0.033 (−2.14)
		G	0.62	0.93	0.79				0.016 (2.40)	0.83 (0.22)	0.033 (2.14)
rs2003813	APOL2/APOL1	C	0.81	0.67	0.74	18	31	49	0.068 (1.83)	0.029 (2.18)	0.0046 (2.83)
		T	0.19	0.33	0.26				0.068 (−1.83)	0.029 (−2.18)	0.0046 (−2.83)
rs2157249	APOL2/APOL1	C	0.19	0.27	0.27	17	32	49	0.041 (−2.04)	0.024 (−2.26)	0.0027 (−3.01)
		T	0.81	0.73	0.73				0.041 (2.04)	0.024 (2.26)	0.0027 (3.01)
rs2413394	APOL2/APOL1	A	0.01	0.19	0.11	2	23	25	*	0.076 (1.77)	0.043 (−2.03)
		G	0.99	0.81	0.89				*	0.076 (1.77)	0.043 (2.03)

AA: African-American sample; EA: European-American sample. The “rs” means SNPs from the dbSNP database.

^*A default value of useful minimum number of family in FBAT is 10.The marker rs2413394 in the African-American sample was not calculated because the number of family was under 10.