Table 6.
3 SNPs Haplotype within the Block A defined by EA |
Haplotype frequency |
Informative family |
Global test (GT) p-value (df, chi-square) |
Allele specific test (AST) p-value (Z) |
||||
---|---|---|---|---|---|---|---|---|
rs9610449 | rs6000200 | rs2016988 | rs2003813 | rs2157249 | ||||
0.00054 (3, 17.6) | ||||||||
C | C | T | 0.52 | 66 | 0.082 (−1.74) | |||
G * | C * | T * | 0.32 | 85 | 0.00011 (3.87) | |||
G | T | C | 0.15 | 45 | 0.013 (−2.48) | |||
Block E (2 SNPs haplotype) defined by AA |
||||||||
0.13 (2, 4.05) | ||||||||
T ** | C ** | 0.81 | 77 | 0.098 (−1.65) | ||||
C ** | G ** | 0.19 | 76 | 0.081 (1.75) |
AA: African-American; EA: European-American; entire sample: African-American, European-American, Chinese and Japanese. Haplotypes with the IF > 10 are not shown for each block because a default value of useful minimum number of family in FBAT is 10.
The most significant haplotype in the combined sample (African-American and European-American).
The most significant haplotype in the African-American sample.