Table 1.
MZ | DZ | |||
---|---|---|---|---|
Within Trait | BN | N* | 3768 | 2634 |
Concordant/Discordant Pairs** | 11 / 63 | 0 / 55 | ||
r (95% CI) | 0.63 (0.47; 0.79) | −0.02 (−0.47; 0.45) | ||
AUD | N* | 4024 | 2860 | |
Concordant/Discordant Pairs* | 55 / 175 | 20 / 141 | ||
r (95% CI) | 0.65 (0.57; 0.73) | 0.42 (0.27; .056) | ||
Cross Trait | Within Twin | N* | 3942 | 2782 |
Concordant/Discordant Diagnoses** | 20 / 339 | 10 / 224 | ||
r (95% CI) | 0.30 (0.18; 0.42) | 0.24 (0.08; 0.40) | ||
Cross Twin | N* | 3882 | 2741 | |
Concordant/Discordant Pairs* | 11 / 346 | 4 / 224 | ||
r (95% CI) | 0.14 (0.00; 0.28) | 0.02 (−0.21; 0.23) |
Note. N*= number of individuals used in the calculation
number of concordant affected pairs and number of discordant pairs used in the calculation
number of twins with both BN and AUD (concordant) and number of twins with only one diagnosis, BN or AUD (discordant). Within trait (“intraclass correlations”) correlations reflect the correlation of bulimia nervosa and alcohol use disorder between members of twin pairs by zygosity group. Cross-trait, within twin correlations reflect the correlation between bulimia nervosa and alcohol use disorder within individuals. Cross-trait, cross-twin correlations reflect the correlations of bulimia nervosa in one twin with alcohol use disorder in the co-twin by zygosity groups