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. Author manuscript; available in PMC: 2013 Aug 7.
Published in final edited form as: Clin Chem. 2011 Oct 6;57(12):1687–1692. doi: 10.1373/clinchem.2011.171314

Table 3. Percentage decrease needed in each assay for statistical significance at various probability thresholds.

Test n Total CV P = 0.5 P = 0.8 P = 0.9 P = 0.95
Serum M-spike 158 11.6 10.5 19.0 23.6 27.5
Measurable serum M-spikea 90 8.1 7.4 13.7 17.2 20.1
Involved immunoglobulin (IgG) 148 13.0 11.7 21.0 26.1 30.3
Urine M-spike 25 35.8 28.9 47.7 56.5 62.9
iFLC 158 34.9 28.3 46.9 55.6 62.0
Measurable iFLCb 52 28.4 23.7 40.2 48.3 54.5
uFLC 157 45.2 35.0 55.9 65.1 71.4
rFLC 157 36.4 36.4 57.7 66.9 73.2
a

Values >10 g/L.

b

Values >100 mg/L.