Table 4. Total, analytical, and biological CVsa.
| Measurable serum M-spikeb |
Urine M-spike (≥200 mg/24 h) |
Measurable serum iFLCc |
Serum IgG | |
|---|---|---|---|---|
| Total CV | 8.1 | 35.8 | 28.4 | 13 |
| Analytical CV | 2.1 | 4.5 | 5.8 | 4.2 |
| Biological CV | 7.8 | 35.5 | 27.8 | 12.3 |
a
Total CVs are from Table 2, analytical CVs are from laboratory validation studies, and biological CVs are derived from the relationship of the biological CV being equal to the square root of the difference of the square of the total CV minus the square of the analytical CV.
b
Values >10 g/L.
c
Values >100 mg/L.