Table 1.
Change in psychiatric rating scales from baseline to week 10 according to treatment group.
| Psychiatric rating scales | |||||||
|---|---|---|---|---|---|---|---|
| Drug treatment group | CGI | PANSS | PANSS-P | PANSS-N | PANSS-G | HAM-A | HAM-D |
| Placebo group mean ± SEM | −0.75 ± 0.22 | −10.25 ± 2.64 | −2.25 ± 0.86 | −2.33 ± 0.85 | −6.17 ± 1.61 | −5.00 ± 1.76 | −5.08 ± 1.25 |
| EGCG group mean ± SEM | −0.64 ± 0.27 | −9.29 ± 3.16 | −2.21 ± 0.72 | −2.43 ± 1.09 | −4.50 ± 1.67 | −3.14 ± 1.71 | −3.643 ± 1.84 |
| Group difference mean ± SEM | −0.11 ± 0.35 | −0.96 ± 4.20 | −0.04 ± 1.11 | 0.10 ± 1.42 | −1.67 ± 2.35 | −1.86 ± 2.46 | −1.44 ± 2.30 |
| (95% CI)a | (−0.84 to 0.62) | (−9.64 to 7.71) | (−2.33 to 2.27) | (−2.83 to 3.02) | (−6.51 to 3.18) | (−6.94 to 3.22) | (−6.19 to 3.31) |
a
From unpaired t-tests; all p-values > 0.05.
CGI, Clinical Global Impression scale–Schizophrenia scale; CI, confidence interval; EGCG, epigallocatechin gallate; HAM-A, Hamilton Anxiety Scale; HAM-D, Hamilton Depression Scale; PANSS, Positive and Negative Syndrome Scale (PANSS); PANSS-G, PANSS - general psychopathology symptoms; PANSS-N, PANSS - negative symptoms; PANSS-P, PANSS - positive symptoms.