Figure 2.

Ethanol MRS intensity increases with exposure in GM and WM. Average ± standard errors in $\frac{[\text{EtOH}]}{[{\text{H}}_2\text{O}]}{\mathrm{\beta }}_{\text{j}}^{\text{GM}}$ (gray filled circles) and $\frac{[\text{EtOH}]}{[{\text{H}}_2\text{O}]}{\mathrm{\beta }}_{\text{j}}^{\text{WM}}$ (open circles) are plotted vs. experimental time points. Ethanol MRS intensity in GM is significantly larger at all subsequent time points than it was in the ethanol-naïve state (asterisks, solid lines). In WM, ethanol MRS intensity is observed to be significantly higher than in the ethanol-naïve state following 9, as well as following 12 months 22 hours free-access drinking (asterisks, dashed lines). The distributions of cumulative ethanol intakes following each drinking period are shown as insets.