For all sites combined, when compared to the p16 positive/HPV16 positive cases, patients with p16 positive/HPV16 negative and p16 negative/HPV16 positive had poorer survival. p16 negative/HPV16 negative status had the worst survival. (p16+ve – p16 positive, p16-ve – p16 negative, HPV+ve – HPV16 positive, HPV-ve – HPV16 negative)