Table 3.

p16, HPV16 and Survival

A) All Sites Combined		N=80	Hazard Ratio	Confidence Interval	p-value
p16	p16+ve	21/80	0.33	0.15 - 0.75	0.007*
HPV16	HPV16+ve	40/80	0.53	0.30 - 0.94	0.029*
p16/HPV	p16+ve/HPV16+ve	12/80	1.00 (ref)
	p16+ve/HPV16−ve	9/80	6.97	1.33 - 36.41	0.021*
	p16−ve/HPV16+ve	28/80	6.82	1.58 - 29.44	0.01*
	p16−ve/HPV16−ve	31/80	8.67	2.04 - 36.85	0.003*
p16 & Race	p16+ve CA	15/78	1.00 (ref)
	p16+ve AA	6/78	1.71	0.33 - 8.86	0.524
	p16−ve CA	25/78	3.78	1.40 - 10.17	0.009*
	p16−ve AA	32/78	2.97	1.12 - 7.85	0.029*
HPV16 & Race	HPV16+ve CA	26/78	1.00 (ref)
	HPV16+ve AA	14/78	1.56	0.63 - 3.86	0.333
	HPV16−ve CA	14/78	2.91	1.26 - 6.70	0.012*
	HPV16−ve AA	24/78	1.79	0.86 - 3.73	0.121
B) OP site only		N=20
	p16+ve	13/20	0.22	0.06 - 0.89	0.034*
	HPV16+ve	10/20	0.2	0.04 - 0.98	0.047*
	p16+ve/HPV16+ve	9/20	1.00 (ref)
	p16+ve/HPV16−ve	4/20	6.98	0.61 - 79.47	0.117
	p16−ve/HPV16+ve	1/20	11.44	0.69 - 191.0	0.09
	p16−ve/HPV16−ve	6/20	10.3	1.20 - 88.33	0.033*

CA - Caucasian American, AA - African American, OP - Oropharynx,

^*significant p-value; p16+ve: p16 positive, p16−ve: p16 negative, HPV16+ve: HPV16 positive, HPV16−ve: HPV16 negative.