Table 2.
An overview of the most common herbal medicines involved in pharmacokinetic CYP interactions with chemotherapeutic drugs
| Herb | Indication | CYP involvment | Effect on metabolism | Reference |
|---|---|---|---|---|
|
Ginko biloba |
Psychostimulant |
2 D6 |
inhibition |
[12] |
| 3 A4 | ||||
|
Aloe vera |
Antioxidant |
3 A |
inhibition |
[13] |
| Antiproliferative | ||||
| Immunostimulant |
2C9 |
|||
|
Green tea |
Immunostimulant |
3 A |
inhibition |
[14] |
|
Saint John’s Wort |
Antidepressant |
3 A4 |
inhibition |
[15] |
| 2 C9 | ||||
| 1 A2 | ||||
| 1 B1 | ||||
| 2 D6 | ||||
|
Ginseng |
Psychostimulant |
3 A |
inhibition |
[16] |
| 2 C9 | ||||
| Immunostimulant |
2 C19 |
|||
| 2 d6 | ||||
|
Echinacea |
Immunostimulant |
3 A |
inhibition |
[17] |
| 2 D6 | ||||
| Garlic | Antioxidant |
3 A |
inhibition | [18] |
| Immunostimulant |
2 C9 |
|||
| Antiplatelet activity | 2 C19 |