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Silencing effect of ssAAV9-shSOD1 vector on mRNA expression level of SOD1. The qRT-PCR of SOD1 mRNA in DRG at 4 weeks (A) and 12 weeks (B) after injection with ssAAV9-shRNA vector shows that superoxide dismutase-1 (SOD1) expression was significantly inhibited (*P < 0.05). There is no significant difference of the expression level of SOD1 mRNA between ssAAV9-shSOD1 and control in the spinal cord (C).
