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Silencing effect of ssAAV9-shSOD1 vector on protein level of SOD1. The SOD1 protein level was reduced in DRG as assessed by Western blot analysis at 4 weeks and 12 weeks after injection (A). Densitometric analysis of Western blot bands confirmed significant downregulation of SOD1 in the injected mice at both 4 and 12 weeks (B). Data are presented as mean ± SEM (*P < 0.05, n = 7 for each group).
