Figure 6.

Suppression of seizure sensitivity by gish is specific to para^bss1 heterozygotes. (A) The percentage of eas flies showing a bang sensitive paralytic behavioral phenotype is not reduced by gish⁰⁴⁸⁹⁵/+. Paralysis is 100% of flies in both experimental (genotype: eas; gish⁰⁴⁸⁹⁵/+) and control siblings (genotype: eas; TM6, Dr/+) genotypes. (B) Electrophysiological recording shows that the seizure threshold of eas is a little greater in a gish⁰⁴⁸⁹⁵/+ background (genotype: eas; gish⁰⁴⁸⁹⁵/+), but there is no significant suppression compared with control siblings (genotype: eas; TM6, Dr/+). (C) Recovery time of para^bss1 homozygotes and hemizygotes is not altered by gish loss-of-function. Depicted are recovery times compared between para^bss1; Df(3R)Ed10639/+ experimental flies and their control siblings (genotype: para^bss1; TM3/+).