Table 2.
Rescue of MPP+-induced neurotoxicity by quinpirole is significantly suppressed by a D2 antagonist haloperidole (10μM).
Treatment | Number of DA neurons per 1,000 cells (+/−SEM) | n |
---|---|---|
Control | 3.90+/− 0.12 | 55 |
MPP+ | 2.47+/− 0.06*** | 28 |
MPP+ + Quin | 3.54+/− 0.27 | 105 |
MPP+ + Quin + Hal | 2.30+/− 0.12*** | 90 |
p≤0.001 (Student t-test)