Figure 1.
Onset of menarche and circulating reproductive hormones in cynomolgus macaques fed a high-soy (SOY) or casein-lactalbumin (CL)-based diet. A: The proportion of post-menarchal monkeys across the study period did not differ by diet. B,C: Serum concentrations of estradiol (B) and progesterone (C) were higher after menarche, with no dietary effect. Values are LSM for n=11-17 monkeys/group (error bars=SEM). The significant main effect is indicated in each panel. a,b Labeled means without a common letter differ (P<0.0005) by LSM Tukey’s HSD test. Body weight was included in the model as a covariate.