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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Adv Drug Deliv Rev. 2013 Apr 24;65(8):1020–1030. doi: 10.1016/j.addr.2013.04.014

Figure 3.

Figure 3

Schematic representation of targeted delivery of Tf-based therapeutic agents to intracellular targets using TfR-mediated endocytosis (a) and across a physiological barrier using TfR-mediated transcytosis (b).