Table 1.

Single marker association results for caries susceptibility in Filipino families and detailed criteria used for analysis of caries phenotypes

Position (base pair)	Marker	Gene	Region	Allele	Frequency	Criterion 1 p value	Criterion 2 p value	Criterion 3 p value	Effect
59837591	rs27565	PART1	intron 3–4	T	0.56	0.00021	0.0022	0.00038	protective
60621839	rs4700418	ZSWIM6	5′upstream	G	0.49	0.0089	0.0041	0.0760	protective
68469923	rs875459	CCNB1	intron 3–4	G	0.61	0.0046	0.0204	0.0019	protective
72798995	rs6862039	BTF3	intron 4–5	T	0.51	0.0084	0.0461	0.0026	risk

Caries experience level	n	Criterion 1		Criterion 2		Criterion 3
		DMFT	n	DMFT	n	DMFT	n
Children, up to 12 years of age	115
Low caries experience		0–2	26	0–1	19	0–3	34
High caries experience		3 or higher	89	2 or higher	99	4 or higher	81
Teenagers,13–19 years of age	104
Low caries experience		0–5	44	0–4	40	0–6	52
High caries experience		6 or higher	60	5 or higher	64	7 or higher	52
Adults, 20 years of age and older	258
Low caries experience		0–8	109	0–7	87	0–9	114
High caries experience		9 or higher	149	8 or higher	161	10 or higher	134

Global p < 0.05 is presented in bold. Underlined p value indicates statistical significance after correction for multiple tests (significance set at p < 0.00035). Definition of caries experience level based on age and DMFT scores in Filipino families.