Table 2. Clinicopathological features of primary Retinoblastoma tumors and gene expression profile by QRT-PCR.
| S.No. | Age/ Sex | Clinicopathological descriptions | PAK2 | MAP1B | RABL3 | RAP2A | GAB1 | MLCK2 | MYOT | CALPAIN7 | BAX | TRAF6 | PDCD7 | DFFB |
| 1 | 2/M | RB, PD, Focal CI<3mm, Pre laminar& Post laminar invasion of ON. | UR | UR | UR | UR | UR | NS | UR | UR | DN | DN | DN | DN |
| 2 | 2/M | RB, UD, CI>3mm, Tumor cells invading in anterior border of sclera. | UR | UR | UR | UR | UR | UR | UR | UR | NS | NS | NS | DN |
| 3 | 2/F | RB, PD, CI>3mm, Pre laminar & Post laminar invasion of tumor. | UR | UR | UR | UR | UR | UR | UR | UR | NS | DN | NS | DN |
| 4 | 2/F | RB, WD, CI<3mm, No invasion of ON. | UR | NS | UR | UR | UR | UR | UR | NS | DN | DN | DN | DN |
| 5 | 6/M | RB, CI>3mm, Tumor cells touching the anterior border of the sclera. | UR | UR | UR | UR | UR | UR | UR | UR | DN | DN | DN | DN |
| 6 | 3/F | RB, MD, CI>3mm, Pre laminar& Post laminar invasion of ON. | UR | UR | UR | UR | UR | UR | UR | UR | DN | DN | DN | DN |
| 7 | 4/M | RB, PD, CI>3mm, Pre laminar& Post laminar invasion, Tumor invasion into anterior, middle& posterior border of sclera. | UR | UR | UR | UR | UR | UR | UR | UR | NS | DN | DN | NS |
| 8 | 1/F | RB, WD, CI<3mm, No invasion of ON | UR | UR | UR | UR | UR | NS | UR | UR | DN | DN | DN | DN |
| 9 | 3/F | RB, PD, No CI, Pre laminar &Post laminar invasion of ON. | UR | UR | UR | UR | UR | UR | UR | UR | DN | DN | DN | DN |
| 10 | 2/M | RB, PD, NoCI, Pre laminar invasion of ON. | UR | UR | UR | UR | NS | NS | NS | NS | DN | DN | DN | DN |
| 11 | 13mon/ M | RB, WD, NoCI, No invasion of ON | UR | UR | UR | UR | NS | UR | NS | UR | DN | DN | NS | DN |
| 12 | 11/F | RB, MD, CI<3mm | UR | UR | UR | UR | UR | UR | UR | UR | DN | DN | DN | DN |
F: Female; M: Male; RB: Retinoblastoma; PD: Poorly Differentiated; MD: Moderately Differentiated; WD: Well Differentiated; UD: Un-Differentiated; CI: Choroid Invasion; ON: Optic Nerve; UR: Up-regulation above 1 fold change (Log 2 ratio); DR: Down-regulation above 1 fold change (Log2 ratio); NS: Not Significant fold change.