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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Pediatr Res. 2013 Jun 3;74(2):127–132. doi: 10.1038/pr.2013.90

Figure 5.

Figure 5

The dependence of formula fat digestion on the combined action of gastric lipase, CEL and PLRP2. In each case, 25 μg of each lipase and 5 μg of colipase were added to the incubation except that no colipase was added during the pre-incubation with gastric lipase. The assays were done on a human formula, Similac Advance 20, with a physiological mixture of bile salts (4 mM). The values are the mean ± SD (n = 3). (No gastric lipase) White bar, formula; Gray bar, CEL; Coarse hatched bar, PLRP2; Fine hatched bar CEL & PLRP2. There is a statistically significant difference among the mean values of the different conditions as determined by one-way ANOVA (F(3,8)= 32.05, P <0.001). *P < 0.05 PLRP2 (0.38 ± 0.08) compared with formula (0.08 ± 0.02) and CEL (0.1 ± 0.04), **P < 0.05 CEL & PLRP2 (0.36 ± 0.04) compared with formula and CEL by the Holms-Sidak post-hoc pairwise multiple comparisons method. (Gastric lipase) White bar, formula; Black bar, gastric lipase; Gray bar, CEL; Coarse hatched bar, PLRP2; Fine hatched bar, CEL & PLRP2. There is a statistically significant difference among the mean values of the different conditions as determined by one-way ANOVA (F(4,10)= 220..03, P <0.001). *P < 0.05 gastric lipase (0.4 ± 0.2) compared to formula (0.06 ± 0.01), **P < 0.05 CEL (1.1 ± 0.1) compared with gastric lipase and formula, †P < 0.05 PLRP2 (1.4 ± 0.1) compared with CEL, gastric lipase and formula, ‡P < 0.05 CEL & PLRP2 (2.3 ± 0.2) compared with PLRP2, CEL, gastric lipase and formula by the Holms-Sidak post-hoc pairwise multiple comparisons method.