Table 5.
Waist circumference and waist-hip ratio in relation to incidence of lung cancer
| No. of Cases | Person-years | Age-adjusted | Multivariablea | Multivariableb | ||||
|---|---|---|---|---|---|---|---|---|
| HR | (95% CI) | HR | (95% CI) | HR | (95% CI) | |||
| Waist circumference (inches) | ||||||||
| <28 | 50 | 137,612 | 1.00 | 1.00 | 1.00 | |||
| 28–29 | 62 | 167,228 | 0.76 | (0.52–1.10) | 0.74 | (0.51–1.08) | 0.81 | (0.55–1.19) |
| 30–32 | 50 | 98,356 | 0.80 | (0.54–1.19) | 0.72 | (0.49–1.08) | 0.83 | (0.54–1.28) |
| 33–36 | 60 | 158,076 | 0.57 | (0.39–0.84) | 0.52 | (0.36–0.76) | 0.63 | (0.41–0.97) |
| 37+ | 63 | 124,960 | 0.77 | (0.53–1.12) | 0.64 | (0.44–0.94) | 0.85 | (0.54–1.35) |
| p for trend | 0.08 | 0.01 | 0.23 | |||||
| Waist-hip ratio | ||||||||
| <0.71 | 46 | 139,769 | 1.00 | 1.00 | 1.00 | |||
| 0.71–0.75 | 52 | 129,728 | 1.17 | (0.79–1.74) | 1.18 | (0.79–1.76) | 1.20 | (0.80–1.78) |
| 0.76–0.80 | 64 | 132,773 | 1.29 | (0.88–1.88) | 1.19 | (0.81–1.74) | 1.25 | (0.85–1.84) |
| 0.81–0.86 | 56 | 134,731 | 1.12 | (0.76–1.65) | 0.96 | (0.65–1.42) | 1.02 | (0.69–1.51) |
| 0.87+ | 63 | 130,396 | 1.51 | (1.03–2.21) | 1.16 | (0.79–1.70) | 1.27 | (0.86–1.87) |
| p for trend | 0.07 | 0.71 | 0.39 | |||||
a
Adjusted for age, education, physical activity, alcohol consumption, parity, age at first birth, family history of lung cancer, geographic region, and pack-years of smoking.
b
Adjusted for covariates listed above and body mass index.