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. Author manuscript; available in PMC: 2013 Aug 8.
Published in final edited form as: J Am Chem Soc. 2004 Feb 18;126(6):1666–1674. doi: 10.1021/ja038381e

Figure 8. Switchback DNA.

Figure 8

The drawing on the upper left shows a four one-half-turn switchback design. 5' ends are indicated by filled circles and 3' ends by arrowheads. Backbones are drawn in blue and red, and helix domain axes are drawn in green. The central upper panel shown the same notion extended to three-half-turn domains. The upper right panel illustrates a stable five one-half-turn domain. The bottom left panel is a rotated version of the upper left panel, with numbered domains that are differently color coded. The panel on the lower right shows that this sequence can assume a nicked PX structure that increases the stacking of the molecule. The nicks are shown away from the crossover points for clarity, but have been found to be near the crossover points.