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. Author manuscript; available in PMC: 2013 Aug 8.
Published in final edited form as: Alcohol. 2012 Mar 24;46(4):371–376. doi: 10.1016/j.alcohol.2011.11.003

Fig. 1.

Fig. 1

A. Nursery reared animals have lower overall brain tissue levels of 5-hydroxyindoleacetic acid (5-HIAA) than mother-reared subjects. Animals that were subjected to maternal separation in the nursery-rearing condition exhibited significantly lower tissue concentrations of 5-HIAA (P = 0.0041). B. Regional analysis (SNpr = substantia nigra pars reticulate, SNpc = substantia nigra pars compacta, Hipp = hippocampus) indicates a trend toward lower 5-HIAA concentrations in striatal regions, with a significant difference in the putamen (p = 0.0184). Open bars represent MR and closed bars represent NR animals.