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. Author manuscript; available in PMC: 2013 Aug 8.
Published in final edited form as: Alcohol. 2012 Mar 24;46(4):371–376. doi: 10.1016/j.alcohol.2011.11.003

Table 1.

Early life stress produces serotonin system alterations that are not influenced by a history of ethanol self-administration.

MR – Naïve MR – EtOH NR – Naïve NR – EtOH
(Tissue content in mean ± SEM in ng/mg wet weight)
5-HIAA 110.4 ± 13.37 143.6 ± 18.93 86.04 ± 11.45 103.5 ± 13.24
5-HT 55.35 ± 7.055 60.21 ± 8.905 54.05 ± 9.388 58.94 ± 8.993
(Ethanol intake in avg daily g/kg)
Ethanol intake 2.18 ± 0.03 2.87 ± 0.03*

No significant differences in monoamine tissue levels were found as a result of ethanol treatment condition in MR and NR animals, p > 0.05 for all comparisons. Drinking data (average daily g/kg, * represents p < 0.05) are presented for the ethanol drinking groups. Data were collapsed within rearing condition for all subsequent analyses.