Table 1.

Response of 10 Mabs to T2-Glc, T-2 toxin, and HT-2 toxin.

	IC50 (ng/mL) a				Cross-reactivity (%) b
Mab	T2-Glc	T-2 toxin	HT-2 toxin	Mab	T-2 toxin	HT-2 toxin
1-2	623 ± 15	614 ± 47	>60000	1-2	101 ± 8	<1.0
1-3	8.6 ± 0.8	6.3 ± 0.6	43.2 ± 7.2	1-3	135 ± 14	19.9 ± 3.3
1-4	13.3 ± 1.7	13.5 ± 0.6	243 ± 22	1-4	99.0 ± 5.0	5.5 ± 0.5
2-5	13.4 ± 0.6	14.0 ± 1.9	33.8 ± 2.8	2-5	96.3 ± 13.1	39.8 ± 3.3
2-11	17.6 ± 0.7	20.2 ± 1.2	562 ± 71	2-11	86.9 ± 5.5	3.1 ± 0.4
2-13	3.5 ± 0.4	3.8 ± 0.1	271 ± 19	2-13	91.6 ± 4.1	1.3 ± 0.1
2-16	13.6 ± 0.3	17.4 ± 1.0	321 ± 16	2-16	78.6 ± 4.9	4.3 ± 0.2
2-17	11.3 ± 0.1	16.7 ± 1.3	118 ± 12	2-17	67.5 ± 5.5	9.5 ± 0.9
2-21	28.2 ± 0.5	23.1 ± 1.0	255 ± 4	2-21	122 ± 5	11.1 ± 0.2
2-44	7.8 ± 0.4	8.5 ± 0.2	28.1 ± 5.4	2-44	91.3 ± 2.6	27.7 ± 5.3

^a Concentration of compound that inhibited binding of the antibody by 50% in CI-ELISA. Values shown were derived from triplicate plates for each antibody and indicate the mean ± 1 standard deviation; ^b Percentage cross reactivity relative to T2-Glc. Cross reaction was calculated as [(IC₅₀ of T2-Glc/IC₅₀ of analog) × 100%].